Based on settlers' accounts the land that came to be known as Pymble was traversed by, and at least periodically inhabited by, what was by that time the "remains" of the Cammeraigal clan or tribe of the Kuringai (also known as Guringai) Aborigines. The Cammeraigal had occupied the land between the Lane Cove River, Hawkesbury and east to the coast. They would travel from grounds at Cowan Creek to the Parramatta River via Pymble - passing west through the land where Pymble Ladies' College now stands, through the Lane Cove Valley and North Ryde.[3] En route they would reportedly hold corroborees at the current site of the Pymble Reservoir on Telegraph Rd and "camped on the hill...at the junction of Merrivale Rd and Selwyn St." [4]

Pymble is named after Robert Pymble (1776–1861), an influential early settler whose 1823 land grant comprised some 600 acres, around half the land of the region. The other half (plus a large part of St Ives) was granted to Daniel der Matthew's, another influential settler who established the first sawmill in the area.  (Wikipedia)